Molecule by Pud&Mun 01 Perfume- Iso E Super (100ml)

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Stagnant water, charcoal, semen... 10 smells that changed the perfume industry". The Telegraph . Retrieved 2017-06-21. a b US 3929677,Hall, John B.&Sanders, James Milton,"Perfume composition and perfume articles containing one isomer of an octahydrotetramethyl acetonaphthone",issued 1975

The fragrance Molecule 01 (Escentric Molecules, 2005) is a specific isomer of Iso E Super, by the company IFF. [19] Its partner fragrance Escentric 01 contains Iso E Super along with ambroxan, pink pepper, green lime with balsamic notes like benzoin mastic and incense. Beyond personal perception, the impact of Iso E Super on others is truly remarkable. It lends an indefinable allure to the wearer, captivating those who encounter its aroma. Its effect is reminiscent of pheromones, drawing attention and fascination without a clear explanation. Belsito; etal. (2013). "A toxicological and dermatological assessment of alkyl cyclic ketones when used as fragrance ingredients. RIFM Expert Panel". Food and Chemical Toxicology. 62: S1-44. doi: 10.1016/j.fct.2013.09.033. PMID 24246175.Iso E Super is produced commercially by Diels–Alder reaction of myrcene with 3-methyl-3-penten-2-one in the presence of aluminium chloride to give a monocyclic intermediate that is cyclized in the presence of 85% phosphoric acid. [6] Synthesis Iso E Super is a molecule that hovers close to the skin to create an indefinable aura around the wearer. The distinction of Iso E Super lies in its design as an aroma-chemical rather than a traditional fragrance. Ordinary fragrances are crafted to project themselves over a wide radius, while Iso E Super is specifically formulated to cling to the skin, effortlessly oscillating between moments of opulence and simplicity. This duality allows it to be at times distinctly noticeable and at other times undetectable, creating an intriguing and ever-changing olfactory experience. The wearer may perceive a subtle, velvety, and woody note that momentarily fades away, only to resurface after some time, enhancing the fragrance's allure and complexity. In 2014 the US National Toxicology Program ( NTP) conducted a 13-week repeat dose toxicity study and found no adverse effects. [17] The International Fragrance Association (IFRA) has published safe use levels for Iso E Super in consumer products. [10]

Klashka; etal. (2013). "Occurrences and potential risks of 16 fragrances in five German sewage treatment plants and their receiving waters". Environ. Sci. Pollut. Res. 20 (4): 2456–71. doi: 10.1007/s11356-012-1120-9. PMID 22945655. S2CID 31312476. No data were available regarding chemical disposition, metabolism, or toxicokinetics; acute, short-term, subchronic, or chronic toxicity; synergistic or antagonistic activity; reproductive or teratological effects; carcinogenicity; genotoxicity; or immunotoxicity. [5]Iso E Super may cause allergic reactions detectable by patch tests in humans [8] and chronic exposure to Iso E Super from perfumes may result in permanent hypersensitivity. In a study with female mice, Iso E Super was positive in the local lymph node assay (LLNA) and irritancy assay (IRR), but negative in the mouse ear swelling test (MEST). [9] Discover the captivating nature of Iso E Super, an aroma-chemical that transcends traditional fragrances. Experience the allure of its sweet cedarwood-like scent and embrace the intrigue it brings to both the wearer and those around them. a b Bonnie L. Carson (2001), "1-(1,2,3,4,5,6,7,8-Octahydro-2,3-8,8-tetramethyl-2-naphthalenyl) ethanone", Review of Toxicological Literature (PDF), National Institute of Environmental Health Sciences The measured Bio Concentration Factor (BCF) is 391L/kg, which is well below the EU limit of 2000 and US limit of 1000 for Bioaccumulation (B) classification. The LogKow for OTNE has been measured to be 5.65. [7] OTNE is registered on all major chemical inventories (US, Japan, China, Korea, Philippines, and Australia) and has been EU REACH registered in 2010. [7]

Given the sensitization classification of OTNE, and its use in fragrances, the International Fragrance Association (IFRA) has published safe use levels for OTNE in consumer products, which have been in effect since August 2009. [14] Environmental data [ edit ]OTNE is the abbreviation for the fragrance material with Chemical Abstract Service ( CAS) numbers 68155-66-8, 54464-57-2 and 68155-67-9 and EC List number 915-730-3. It is a multi-constituent isomer mixture containing: OTNE is classified as H410 Very toxic to aquatic life with long-lasting effects ( EU-CLP) or R51/53 Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment (EU DSD). [7] OTNE has been recommended for inclusion in an update for the EU Fragrance Allergens labelling for cosmetic products based on a small number of positive reactions in dermatological clinics of around 0.2% to 1.7% of patients tested in three studies [18]