PectaSol Modified Citrus Pectin Powder Super-Nutrient to Support Cellular & Immune Health, Joint Support - 454 Grams - Formulated by Dr. Isaac Eliaz of ecoNugenics

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Nangia-Makker, P., Hogan, V., Honjo, Y., Baccarini, S., Tait, L., Bresalier, R., et al. (2002). Inhibition of human cancer cell growth and metastasis in nude mice by oral intake of modified citrus pectin. J. Natl. Cancer Inst. 94, 1854–1862. doi: 10.1093/jnci/94.24.1854

Modified citrus pectin inhibits breast cancer development in Modified citrus pectin inhibits breast cancer development in

After polarization or treatment, the cells were cultured in serum-free medium for 48 h. The medium supernatant was collected, centrifuged (1000 × g, 5 min) and filtered through a 0.22-μm syringe filter, and stored at −80 °C until use. In vitro angiogenesis or vascular mimicry assay We further explored the effect of MCP on LPS and IFN-γ induced M1-like polarization of THP-1. The result showed that MCP had no obvious inhibitory effect on the survival of M1-like THP-1 (Fig. 5f). Meanwhile, the expression of M1 marker CD86 showed no significant change in the presence of MCP by flow cytometry (Fig. 5g), indicating that MCP did not affect the M1-like polarization of THP-1. The tumor-promoting functions of TAM were reduced after the inhibition of M2-like polarization by 0.05% MCP PectaSol is ideal for adults seeking comprehensive daily support and defense for optimal cell, tissue, and organ function, long-term immune health, and total-body wellness.*

Paik JY, Jung KH, Lee JH, Park JW, Lee KH. Reactive oxygen species-driven HIF1α triggers accelerated glycolysis in endothelial cells exposed to low oxygen tension. Nucl Med Biol. 2017;45:8–14. PectaSol-C® Professional is shown in over 75 published studies to deliver broad-spectrum benefits for our most critical areas of health—from cellular regulation to immune response, cardiovascular and kidney function, and more. People who take PectaSol-C Professional frequently report improvements in energy, mental clarity, and immune function, reduced joint stiffness and greater mobility, improvements in detoxification, cellular function, and overall general wellbeing,*

PectaSol Modified Citrus Pectin Powder Super-Nutrient to PectaSol Modified Citrus Pectin Powder Super-Nutrient to

Pectin organization and composition in plant primary cell wall depend on the growth state of the plant, on the tissues and on the plant species. Its synthesis is a complex process involving numerous enzymes that are just becoming to be identified ( Atmodjo et al., 2013). Biological Activities of Oligogalacturonides in Plants Modified citrus pectin inhibits breast cancer development in mice by targeting tumor-associated macrophage survival and polarization in hypoxic microenvironment Avivi-Green, C., Polak-Charcon, S., Madar, Z., and Schwartz, B. (2000b). Apoptosis cascade proteins are regulated in vivo by high intracolonic butyrate concentration: correlation with colon cancer inhibition. Oncol. Res. 12, 83–95. doi: 10.3727/096504001108747558 Micrometastasis that transforms into clinically relevant secondary tumors eventually comes to depend on the development of new blood vessels via angiogenesis, the fifth and final rate-limiting step in metastasis. Galectin-3 promotes angiogenesis by serving as a chemoattractant for endothelial cells and in The exact chemical structure of pectin is still under debate. Pectins are a family of covalently linked galacturonic acid-rich polymers. Until now, three main pectic polysaccharides have been isolated from plant wall whose structure has been identified. They are homogalacturonan (HG), rhamnogalacturonan-I (RG-I) and substituted galacturonans (GS).

Citation: Leclere L, Van Cutsem P and Michiels C (2013) Anti-cancer activities of pH- or heat-modified pectin. Front. Pharmacol. 4:128. doi: 10.3389/fphar.2013.00128 luc metastasis tumor mouse model: 1 × 10 5 4T1-luc cells (1 × 10 5/100 μL/each mouse) were intravenously injected to each mouse by tail vein. MCP (low-dose: 350 mg/kg every day; high-dose: 700 mg/kg every day) was given orally at once a day, clodronate liposomes (100 μL/10 g) was administered intravenously every 3 days. Each treatment was performed for consecutive 21 days.

PectaSol-C (Modified Citrus Pectin) 150g – ecoNugenics

The inflammatory mediators (monocyte chemoattractant protein-1, osteopontin, cd68, cd80, cd44, and cd45) were elevated in spontaneously hypertensive rats and attenuated by MCPWith over 75 published studies, PectaSol-C® Professional is the original and only proven form of modified citrus pectin, derived from citrus pith and modified to precise molecular weight and structure. This specialized modification process ensures bioavailability via absorption into the circulation, and gives PectaSol-C professional its’ broad-spectrum bioactivity resulting in systemic benefits for healthy cell, tissue, and organ function.* Platt, D., and Raz, A. (1992). Modulation of the lung colonization of B16-F1 melanoma cells by citrus pectin. J. Natl. Cancer Inst. 84, 438–442. doi: 10.1093/jnci/84.6.438 The number of fecal lactobacilli in the MCP alginate probiotic-treated mice significantly increased